SOC Drugs

# 1. Target: GSR

Drugs

Model Evidence

6 regulons containing the target(s), GSR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


Drugs in GBM Trials

# 1. Target: RRM2

Drugs

Model Evidence

12 regulons containing the target(s), RRM2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


2. Target: FNTA,FNTB

Drugs

Model Evidence

14 regulons containing the target(s), FNTA,FNTB are overactive in this patient.

Hallmarks Enrichment

HALLMARK_OXIDATIVE_PHOSPHORYLATION

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


3. Target: WEE1

Drugs

Model Evidence

13 regulons containing the target(s), WEE1 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


4. Target: JAK1,JAK2

Drugs

Model Evidence

21 regulons containing the target(s), JAK1,JAK2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


FDA Approved Drugs

# 1. Target: APP

Drugs

Model Evidence

41 regulons containing the target(s), APP are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


2. Target: TNFRSF1A

Drugs

Model Evidence

16 regulons containing the target(s), TNFRSF1A are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


3. Target: PLA2G2A,PLA2G5

Drugs

Model Evidence

8 regulons containing the target(s), PLA2G2A,PLA2G5 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


4. Target: JAK1

Drugs

Model Evidence

4 regulons containing the target(s), JAK1 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


5. Target: TNC

Drugs

Model Evidence

10 regulons containing the target(s), TNC are overactive in this patient.

Hallmarks Enrichment

HALLMARK_TNFA_SIGNALING_VIA_NFKB

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


6. Target: CA2

Drugs

Model Evidence

15 regulons containing the target(s), CA2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


7. Target: UGCG

Drugs

Model Evidence

51 regulons containing the target(s), UGCG are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


8. Target: ABL1

Drugs

Model Evidence

5 regulons containing the target(s), ABL1 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


9. Target: OXTR

Drugs

Model Evidence

11 regulons containing the target(s), OXTR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


10. Target: BSG

Drugs

Model Evidence

2 regulons containing the target(s), BSG are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


11. Target: NDUFA13

Drugs

Model Evidence

5 regulons containing the target(s), NDUFA13 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


12. Target: TSG101

Drugs

Model Evidence

2 regulons containing the target(s), TSG101 are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


13. Target: ABAT

Drugs

Model Evidence

17 regulons containing the target(s), ABAT are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


14. Target: NQO1

Drugs

Model Evidence

2 regulons containing the target(s), NQO1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


15. Target: PLA2G2A

Drugs

Model Evidence

2 regulons containing the target(s), PLA2G2A are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


16. Target: ELN

Drugs

Model Evidence

1 regulons containing the target(s), ELN are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


17. Target: TRPV4

Drugs

Model Evidence

1 regulons containing the target(s), TRPV4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


18. Target: FNTA,FNTB

Drugs

Model Evidence

14 regulons containing the target(s), FNTA,FNTB are overactive in this patient.

Hallmarks Enrichment

HALLMARK_OXIDATIVE_PHOSPHORYLATION

Literature Evidence

Glioblastoma Clinical Trials

Network Plots


19. Target: HSPA8

Drugs

Model Evidence

28 regulons containing the target(s), HSPA8 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


20. Target: RRM2

Drugs

Model Evidence

12 regulons containing the target(s), RRM2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


21. Target: MAPK1,MAPK3

Drugs

Model Evidence

18 regulons containing the target(s), MAPK1,MAPK3 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


22. Target: ANGPT2

Drugs

Model Evidence

23 regulons containing the target(s), ANGPT2 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_TNFA_SIGNALING_VIA_NFKB

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


23. Target: JAK1,JAK2

Drugs

Model Evidence

21 regulons containing the target(s), JAK1,JAK2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


24. Target: SLC6A9

Drugs

Model Evidence

13 regulons containing the target(s), SLC6A9 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


25. Target: GSR

Drugs

Model Evidence

6 regulons containing the target(s), GSR are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


26. Target: HRH1

Drugs

Model Evidence

41 regulons containing the target(s), HRH1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


27. Target: JAK2

Drugs

Model Evidence

17 regulons containing the target(s), JAK2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


28. Target: ATP1A1

Drugs

Model Evidence

63 regulons containing the target(s), ATP1A1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


29. Target: SOD1

Drugs

Model Evidence

5 regulons containing the target(s), SOD1 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


30. Target: ACVR2B

Drugs

Model Evidence

5 regulons containing the target(s), ACVR2B are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


31. Target: CA2,CA4

Drugs

Model Evidence

15 regulons containing the target(s), CA2,CA4 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


32. Target: ANGPT1,ANGPT2

Drugs

Model Evidence

23 regulons containing the target(s), ANGPT1,ANGPT2 are overactive in this patient.

Hallmarks Enrichment

HALLMARK_TNFA_SIGNALING_VIA_NFKB

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

Network Plots


33. Target: EEF2

Drugs

Model Evidence

9 regulons containing the target(s), EEF2 are overactive in this patient.

Hallmarks Enrichment

None

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


34. Target: HRH1,SLC6A2

Drugs

Model Evidence

41 regulons containing the target(s), HRH1,SLC6A2 are overactive in this patient.

Literature Evidence

No additional evidence was found

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots


35. Target: ANGPT2,VEGFA

Drugs

Model Evidence

28 regulons containing the target(s), ANGPT2,VEGFA are overactive in this patient.

Literature Evidence

Glioblastoma Clinical Trials

No glioblastoma clinical trials were found for these drugs.

Network Plots

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